NextGenSeek Stories To Read This Week (1/10/2014): MiSeqDx, BGI, Genomics Guide, WGS in Class, Stat. Learning

It is not a new year, if there is no resolutions to be made. One of my resolutions is to resurrect the “NextGenSeek Stories To Read This Week” posts linking to the interesting stories. And this week’s stories features the genome factory BGI,  Illumina’s MiSeqDx, Genomics Guide, Computing Guide, Everybody loves Illumina, Everybody wants Oxford Nanopore,  WGS in Class, and Statistical Learning

Blame it on the new year. Many popular websites have stories on next-gen sequencing.  

New Yorker has a big feature on BGI. Full article is not free. Here is a snippet.

LA Times is on MiSeqDX

LA Times has a story on Illumina’s MiSeqDX.  In November last year, FDA approved Illumina’s MiSeqDX, Illumina’s diagnostic version of its benchtop sequencer MiSeq, for marketing. MiSeqDX is alread in UK market and is exptected to cost 20%-30% more than MiSeq’s price. Here LA Times’ story

Aeon Magazine gets a peek at PacBio behind the scenes among many other technologies.

Eric Schmidt (not Eric Schadt) predicts that 2014 belongs to sequencing and smartphones.

A must read guid to “Genomics Research” on PLOS Biology.

And another must read guide on “Scientific Computing” in PLOS Biology

Everybody Loves Illumina and Everybody Wants a Nanopore

If there is any doubt, GenomeWeb’s annual survey shows again that Illumina leads all the way in the sequencing market share.  Illumina has 70% of NGS market and compared to last year it gained slightly. On the other hand, Life Technologies lost 8% of its market share and now stands at 16% market share.

Another surprising outcome from the survey is that almost everybody wants a Oxford Nanopore :). 45% of 62 participants who are considering buying a next-gen sequencer would like to buy Oxford Nanopore Technologies’ MinIon, and 45% for a GridIon.

(Free with registration using academic/non-profit email address.)

Whole Genome Sequencing in the class room

Just a year ago, Icahn School of Medicine at Mount Sinai (ISMMS), offered two semester long courses on “Introduction to Human Genome Sequencing”, and  “Practical Analysis of Your Personal Genome” to its medical students. The key component of the course is to sequence their genome during the class and analyze their own whole genome sequence data.

In case you wondered what happened to the course and how did the students react to it, the team has written up  the experience of WGS outside the clinic and published as a paper in genomic medicine. Check out

Ewan Birney has his thoughts on the new media yes science (yes, blogging and twitter) in his blog EWAN’S BLOG: BIOINFORMATICIAN AT LARGE.

 Rob Tibshirani Does It again

Rob Tibshirani team has made thir second book on statistical learning freely available.  Free #PDF of  the new book, An Introduction to Statistical Learning with Applications in R by James, Witten, Hastie and Tibshirani is available at Gareth James website.

The new book is kind of  “The Elements of Statistical Learning” for the dummies :)  Free pdf of Tibshirani is first book is available here.

Not just that. If you are interested in learning from them, now you don’t have to shell out over $1500 and attend one these. Tibshirani and Hastie are offering a free online course on Statistical Learning in Stanford.    Sign up at

Staying on learning statistics online, check out Raefael Irizarry and Mike Love’s

a HarvardX online course.




  1. The link ‘Best Practices for Scientific Computing’ is broken:

  2. nextgenseek says:

    thanks for catching that. fixed now.

  3. That Best Practices link is still broken. The title and href attributes are swapped.

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