What a week for Illumina and sequencing. Illumina launched two sequencers: one for taking over the sequencing in an individual lab and the other for sequencing the world. Actually, the week started with the big news from Regeneron’s plan to sequence 100,000 individuals, But boy, that news was completely washed by Illumina-geddon.
NextGenSeek stories to read this week covers the ground on what people think about Illumina’s offensive move to keep its No. 1 position in the sequencing market and bringing life back to the “$1000 genome” meme. In addition, we have stories about free PacBio sequencing and its road map for the year 2014.
Illumina-calypse: Blog posts on HiSeq X Ten, NextSeq 500, and $1000 genome
- Mick Watson on Opinionomics: llumina destroy the opposition again – almost….
- Mass Genomics: Illumina’s New NGS Platforms
- CoreGenomics: Illumina’s christmas presents
- CoreGenomics: HiSeq X Ten: only Human Genomes?
- Omics! Omics!: Illumina’s New Lineup
- Mick Watson on Opinionomics: 7 reasons why the NextSeq 500 is a strange choice
- Nature’s Erika Check Hayden: Is the $1,000 genome for real?
- Glenn Lockwood gives a great perspective on what to expect on the computational side of things if “$1000 genome” becomes a reality. Read the awesome post titled, The $1000 Genome – A Computational Perspective
NextGenSeek’ coverage on Illumina’s new sequencers.
- Reactions to Illumina Blitz – NextSeq 500 and HiSeq X Ten on Twitter
- A First Look at Illumina HiSeq X Ten and NextSeq 500
- How Does a Single HiSeq X Compares With HiSeq 2500?
- How Does NextSeq 500 Compare With MiSeq and HiSeq?
- What is the Price of NextSeq 500 and HiSeq X Ten?
PacBio offered to sequence your genome for free, if you could convince them that your genome of interest is the most interesting genome in the world and you attended PAG XXII 2014.
- PAG XXII 2014 “The Most Interesting Genome in the World” Grant Competition: 40 SMRTcells, enough for genome up to ~100Mbp
PacBio also unveiled its vision/goals for this year. Among other things PacBio hopes to gain ~4-fold increase in the throughput per SMRT Cell to get 10-15kb average read lengths and produce over 1 Gb data per SMRT Cell. PacBio hopes to reach these goals while keeping the consensus accuracy high and with no bias. PacBio is confident that the
combination of sequencing chemistry upgrades through polymerase and nucleotide engineering, improvements in the polymerase loading efficiency, and software upgrades
will help reach these goals. Check PacBio blogpost for details.
Regeneron’s human genetics initiative
- Regeneron launched new human genetics initiative with a plan to sequence 100,000 individuals.
Among other genomics news in this week, here are a few interesting stories.
- Bloomberg’s story on New born genome sequencing.
- Venture Beat: Genetics prof: Why I won’t waste my money on a DNA test in 2014
- BGI’s rule of cloning: Clone, if tastes good. Clone, if it looks good. BGI On PR Offense: BBC Reports on BGI
- JP Morgan Healthcare Conference, Day One: Thermo Fisher, Agilent, Qiagen, Genomic Health, Myriad, SomaLogic
- Perspective in Science: Frederick Sanger (1918–2013) by Sydney Brenner