Illumina launches iSeq 100 for $20k at JPM 2018

Illumina's smallest desktop sequencer: iSeq 100

Illumina Launches iSeq 100

Illumina launched a new sequencer iSeq 100 at this year’s JPM.  iSeq 100 can sequence 4 million reads per run, can sequence 2x 150bp with maximum throughput of 1.5Gb per run. iSeq 100 is initially known as Project Firefly and uses CMOS semiconductor technology with SBS.

iSeq 100 is the smallest desktop sequencer in Illumina’s  portfolio and it is primarily focused for providing sequencing solutions to smaller projects, like small genome sequences, targeted gene sequencing, and long-range amplicon sequencing. Illumina advises

Use the iSeq 100 System to conduct smaller projects, avoid running small sample batches on high-throughput instruments, evaluate libraries before a large-scale run, or perform a proof-of-principle study.

Launching iSeq 100 at JPM 2018, Francis deSouza, President and Chief Executive Officer at Illumina said

For under $20,000, any researcher can have access to the accuracy of an Illumina sequencer in their lab. The iSeq 100 offers robustness and reliability for a broad range of applications ranging from germline and somatic tumor profiling to 16S microbial analysis and targeted gene expression.

Dr. Pardis Sabeti, Professor of Immunology and Infectious Disease at Harvard T.H. Chan School of Public Health and a Broad Institute Member

The addition of the iSeq 100 has great potential to transform infectious disease surveillance . We anticipate that our lab researchers will use it to focus on infectious disease monitoring. We have seen examples of how Illumina benchtop systems, like the MiSeq, were instrumental in understanding and addressing disease outbreaks. We believe the accuracy of the iSeq 100, coupled with the low cost and small footprint, will allow us to introduce NGS capability where it is needed most.


  1. […] bed by that time); he also included links to coverage by Matthew Herper’s piece at Forbes, NextGenSeek, and Bio-IT World, GenomeWeb, and Illumina’s stock climbed to a high of $245.74 on the iSeq […]

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