Illumina Sues Oxford Nanopore




In case you missed it, Illumina announced that it is Oxford Nanopore Technologies for violating Illumina’s two patents on nanopore sequencing in Oxford Nanopore’s MinION and PromethION devices. Illumina press release says that The lawsuits are based on U.S. Patent Nos. 8,673,550 and 9,170,230, which are entitled “MSP NANOPORES AND RELATED METHODS.”Illumina has exclusively licensed the […]

AGBT 2016 Link Roundup #AGBT16




AGBT 2016, the four days of genomics fun ended over the last weekend  For the first time, AGBT had designated three official bloggers (James Hadfield, Dale Yuzki, Meredith Salisbury,) blogging during the conference. James Hadfield of CoreGenomics blog was prolific with over 12 blog posts during the conference. Here is a link round-up covering blog posts, slides,  and storified tweets. […]

10X Genomics is on a roll: Chromium System for 3′ single-cell RNA-seq on 48K cells, haplotyping and assembly




The new year has begun with a bang for 10X Genomics, one of the hottest genomics technology company. It all started last year, when 10X Genomics, a stealthy California-based company, made waves with raising $55.5 M with the lofty goal of changing the definition of sequencing. At last year’s AGBT (AGBT 2015) , 10x Genomics […]

Read Until: Real time selective sequencing using Oxford Nanopore MinION




AGBT 2016 is happening now and it has been two years since we heard about the first MinION experiment at AGBT 2014. It has been two years since Oxford Nanopore selected participants for its MinION early access program. And  Oxford Nanopore has come a long way since the last two years. Two very interesting papers […]

Cataloging Splice Junctions in all Human RNA-seq data from Sequence Read Archive




One of the biggest sources of complexity in transcriptomes come from ubiquitous splicing. Our knowledge about the prevalence of alternative splicing has greatly increased from our ability to directly sequence the transcritome by using RNA-seq technology. Granted that to fully characterize the isoforms resulting from splicing, one needs long-read transcriptome sequencing. However, the abundance of […]