All Things Illumina Sequencing Methods




Are you interested in learning about all the applications of Illumina Sequencing methods? or a specific non-standard applications of Illumina sequencing? More specifically want to learn about the methods/technology used, related library prep. kits available, pros and cons of the assay? Illumina is out to help you find the right sequencing method and the right […]

Two Publications on NGS in Critical Care




One of the interesting talks at this year’s AGBT (AGBT 2014) was from Joe DeRisi, a microarray technology pioneer and a professor at UCSF. DeRisi’s talk covered a feel good success story on how Next-Gen Sequencing was useful in finding the cause of a 14 year old boy suffering from acute encephalitis. The boy suffered […]

Hacking Illumina GA IIx to Study RNA-Protein Interactions




Although RNA-Protein binding is very important in many biological processes, like splicing & many post-transcriptional processes, there are not that many high-throughput assays to study Protein-RNA interactions. Contrast this to the advances in DNA-Protein interactions.  Nature Biotechnology has an interesting paper from Greenleaf group at Stanford, that hacked Illumina GA IIx to study RNA-binding in […]

NGS in Critical Care: A Feel Good Story




Joe DeRisi from UCSF gave a talk at AGBT 2014 on the use of Next-Gen Sequencing technology in critical care as an example.  It is a great story, but did not get much attention in social media immediately as the talk happened to be on the same day as Oxford Nanopore data talk by David […]

NextGenSeek Stories To Read This Week (1/17/2014): Illumina, HiSeq X, NextSeq 500, Roadmaps




What a week for Illumina and sequencing. Illumina launched two sequencers: one for taking over the sequencing in an individual lab and the other for sequencing the world. Actually, the week started with the big news from Regeneron’s plan to sequence 100,000 individuals, But boy, that news was completely washed by Illumina-geddon. NextGenSeek stories to read […]