Paper Summary: Systematic bias and batch effects in single-cell RNA-Seq data




Single Cell RNA-seq technology has gained a lot of traction in the last few years, as it can help address a variety of interesting biological problems, ranging from studying development to cancer heterogeneity.  Since the first paper demonstrating the feasibility of single cell transcriptomics with, the number of cells one could assay is also increasing […]

Tips for Next-Gen Sequencing Experiment Design: Randomization




If one aspect of Next-Gen sequencing experiments is missing “big” attention, one can immediately point to “good design principles” for Next-Gen Sequencing experiments. Although, there is a lot of computational/statistical methods are coming up for analyzing Next-Gen Sequencing data, it looks like there are not that many resources for designing NGS experiments. At least it […]