Paper Summary: Fast and accurate single-cell RNA-seq analysis using equivalence class counts

One of the most common applications of single-cell RNA-seq data is to use it to characterize the heterogeneity of  cell populations and identify new cell types or sub-populations.  Typically one uses single-cell RNA-sequencing (RNA-seq) data, quantify gene expression on all cells and use the common gene-expression profile among the cells to characterize the cell-to-cell heterogeneity by […]

Illumina Announces MiniSeq, a new benchtop sequencer

Illumina announced MiniSeq, a new benchtop sequencing system, at this year’s JPM. With MiniSeq, Illumina hopes to offer NGS workflow solution for every lab. MiniSeq is priced at $49,500 USD, to make it easy for any laboratory to adopt NGS. The MiniSeq System is expected to be available early in the first quarter of 2016. MiniSeq […]

AGBT 2016 Schedule is here

Advances in Genome Biology and Technology (AGBT) Meeting,  one of the most anticipated genomics meetings’ full schedule is available now. This year’s main AGBT conference is from 10th February to 13th February, at JW Marriott Orlando, Grande Lakes Orlando, Florida. (Notice the venue change just for this year).  Starting from this year, AGBT has two meetings one […]

HISAT2 for aligning reads against human population

HISAT2, the next iteration of HISAT – the splice-aware low memory alignment program by Daehwan Kim from Steven Salzberg’s team is out. Actually, the beta version of HISAT2 has been available since September, but somehow missed it until HISAT2 was presented as talk at #GI2015. HISAT2 is not just the next iteration of HISAT, HISAT2 can do […]

Software tools for Oxford Nanopore sequence data

Nature Methods has a nice technology feature on Oxford Nanopore,  MAP program, and the experiences of 1000’s of researchers who were part of Oxford Nanopore’s MAP program. Nanopores: a sequencer in your backpack Among  other interesting things about Nanopore sequencing, it also has a list of software tools developed for analyzing Oxford Nanopore sequence data […]